The Institute of Neurological Recovery® provides pioneering neurological treatment approaches for select patients with chronic stroke, traumatic brain injury, and related neurological disorders.
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60 Minutes Australia
In a landmark investigative feature, 60 Minutes Australia documented the incredible journeys of stroke survivors who experienced life-changing recoveries at the Institute of Neurological Recovery®.
The Institute of Neurological Recovery pioneered the breakthrough perispinal etanercept treatment for chronic stroke and brain injury in 2010. Since then, the Institute has treated more than 5,000 patients, including those with ischemic, hemorrhagic, and brainstem stroke; traumatic, hypoxic, intra-operative, and post-cardiac arrest brain injury; and cerebral palsy.

Following perispinal etanercept treatment, the peer-reviewed medical literature includes reports of improvement in chronic post-stroke motor impairment, spasticity, sensory impairment, cognition, behavioral function, aphasia, shoulder pain, and central post-stroke pain.
Peer-reviewed reports following perispinal etanercept treatment describe improvement in walking, motor impairment, spasticity, pain, balance, coordination, cognition, speech and language, and sensation.
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Since 2006, the INR® has published a growing library of peer-reviewed scientific articles documenting its breakthroughs in the field of neuroinflammation, reshaping how chronic stroke, brain injury, and cerebral palsy are understood.
Edward Lewis Tobinick, M.D. is an American physician, inventor, and scientist. Dr. Tobinick is the inventor of the breakthrough perispinal etanercept (PSE) stroke treatment


Complete the contact form and a member of our team will be in touch shortly—typically within the next business day.

A member of our team will provide more information on the treatment, answer your questions, and collect the patient's medical history to assess potential eligibility for care.

After reviewing your paperwork and medical records, we'll schedule a phone consultation with an INR medical provider to discuss your medical history, answer all your questions, and determine if you're a candidate for treatment.

If the patient is determined to be eligible for treatment, our team will coordinate scheduling for the in-person treatment appointment and provide instructions regarding any required lab work that must be completed beforehand.
Perispinal etanercept (PSE) is a method of targeting detrimental neuroinflammation using etanercept, a special anti-inflammatory drug, delivered utilizing a novel, non-invasive injection method.
No, it is not too late. Neuroinflammation can last for years, or even decades, after brain injury. Life-changing neurological improvements following perispinal etanercept treatment performed weeks, months, years, or even decades after stroke or brain injury are not uncommon.
Yes. All treatments are performed exclusively at our clinic in Boca Raton, Florida. Patients travel to us from across the United States and around the world.
No, treatment is self-pay and is not covered by insurance. Our team can discuss cost and answer questions during the consultation process.
Perispinal etanercept (PSE) is NOT experimental. PSE has been used to treat more than 5,000 chronic stroke patients since 2010 at the Institute of Neurological Recovery.
PSE is NOT a spinal injection. The small needle utilized is much too short to reach the spinal canal or the epidural space.
Receive detailed information regarding the Institute’s unique, patented, anti-inflammatory treatment. We currently treat and accept new patients from around the world, even years or decades after stroke or traumatic brain injury.
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