Stroke Recovery with Perispinal Etanercept: Rapid Improvement in Mobility & Balance

About This Video

A patient who suffered a stroke in October 2023 returns for a follow-up evaluation four months after receiving her second Perispinal Etanercept (PSE) treatment.

The video documents the ongoing progress observed by the patient and her family, along with real-time functional tests evaluating changes in her foot alignment, balance, walking mechanics, and hand-eye coordination.

Patient-Reported Changes Featured in This Video

  • Spasticity & Joint Alignment: The patient’s family notes a reduction in muscle spasticity following treatment. Her right foot, which previously turned inward, demonstrated improved alignment, leading to reduced knee hyperextension during movement.
  • Gait Mechanics & Balance: Clinical demonstrations highlight improvements in dorsiflexion (the ability to lift the right foot and toes), allowing for safer and more reliable walking, improved single-leg balance, easier backward/sideways movement, and a smoother bending motion.
  • Footwear Independence: Due to improved leg strength and foot position, the patient was able to transition from specialized hiking shoes back to standard tennis shoes.
  • Fine Motor Coordination: Enhanced hand-eye coordination and finger dexterity allowed the patient to resume playing the clarinet, which she demonstrates during the video.
  • Mobility & Jogging: The patient reports a more natural feeling during higher-level physical activity, including jogging.
Read Video Transcript

*Transcript generated by YouTube

When did you have your stroke? October 18th, 2023. Ischemic and I have small vessels. And today you are returning to our office 4 months after your last period spinal attack treatment. How many treatments have you had so far? I’ve had two. Yeah, within 5 minutes her spasticity was gone. On the second shot, her right foot was turned inward slightly and after the shot, it straightened out which made walking better for Better, right. Her gait has gotten better. She wasn’t able to wear regular shoes for a while there. She had to wear the the hike shoes. And now she’s been able to get back the strength so she can go back to regular shoes. That’s true. tennis shoes Right. And it makes walking much better for does. It it does lessen the hyperextension of my knee. Her hand, she’s able to play the clarinet much better. hand-eye hand-eye connection, coordination is much improved. So yes, I can play my clarinet again. I can know I can chart that easily when I’m playing. That’s really a good thing. The more I practice the the better my hand-eye coordination gets. That that seems to definitely be improving.

Fingers off. These fingers are off here.

What’s wrong with my fingers? I want to see I’ll go down and see. Just go down to one.

And be playing the pie in the face polka by Henry Mancini from the movie The Great Race.

[Patient plays instrument]

And considering where you were at a year or two ago, you’ve come a long way and these shots have really helped get the edge. You did great, hon.

I just know it’s working. Well, it’s worth every penny just to see you getting better. Yeah, it’s good to get better.

Definitely the right side is up higher. That’s really good. I could feel that in my foot. Yeah, that’s always the tough one. We can never get that one up, but it’s higher. It is higher. Look at that. That means exercise will really I’m seeing your toes on your right side. Help a lot. Your toes on your right side are going up. They weren’t before. They are going up.

Oh, wow. That is great. I think that’s a real improvement. Absolutely. It will make your walking much more reliable. And your balance.

That is so much better of walk. Yeah. That’s better. It’s better. That is better. Look at that. It is better. See. [clears throat] Balance is more prominent now than it was before. I have not been on balance on this leg that time frame. That’s better, too. That’s longer than what you were doing. There it is. Look at that. That’s pretty much normal. I mean, that did It did affect the the foot. Mhm. That is exciting. Thank you very much. Oh, thank you so much. This is wonderful. I’ve been waiting 2 and 1/2 years for this. Well, that knee The knee is definitely better. Walking backwards is better. That’s a lot easier.

And sideways. Hey, my knee is in. I can tell. Look at that. Oh, anyway before anyway, I knew it was out. I could exercise for the next 20 years and never have seen this. It’s a miracle.

Yes. Yeah. It is.

God is good to us all. This is great. Well, I’m feeling the difference now. It really is. I’m actually feeling it. You’re doing pretty good with running, too. Yeah, it’s better. Running’s getting better. Yeah. And that’s feeling more natural when I’m running. Okay, now when I bend, it’s all all one motion. That is so much better. Just the way it should be. That’s the best thing about this shot. It works, and you don’t have any side effects. There’s no side effects, and it works fast. Very fast. It’s not like you’re waiting a month to see some results. You see it within [snorts] about 5 10 minutes. That was what it means to It’s all just amazing. It’s truly amazing.

Thank you very much. What a happy occasion.

Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

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Frequently Asked Questions

Perispinal etanercept is a method of targeting detrimental neuroinflammation using etanercept, a special anti-inflammatory drug, delivered utilizing a novel, non-invasive injection method.

Perispinal etanercept is NOT experimental. Perispinal etanercept has been used to treat more than 5,000 chronic stroke patients since 2010 at the Institute of Neurological Recovery.

Perispinal etanercept is NOT a spinal injection. The small needle utilized is much too short to reach the spinal canal or the epidural space.

No, it is not too late. Neuroinflammation can last for years, or even decades, after brain injury. Life-changing neurological improvements following perispinal etanercept treatment performed weeks, months, years, or even decades after stroke or brain injury are not uncommon.

Referrals are not required. The Institute of Neurological Recovery has received, and welcomes, referrals from neurologists, speech pathologists, physical therapists, occupational therapists, primary care physicians, online stroke groups, and, of course, patients and their family members.

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